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Lethal plague outbreaks in Lake Baikal hunter-gatherers 5,500 years ago
Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10540-5Analyses of ancient DNA from hunter-gatherers near Lake Baikal in southeast Siberia around 5,500 years ago indicate that highly …
Spatial distribution of the proteome in the human body and in cancers
Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10660-yA spatially resolved map of the human proteome across a variety of healthy tissues and cancers provides wide-ranging insights …
A mosaic of whole-body representations on the human precentral gyrus
Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10653-xA comprehensive map of the human motor cortex at single-neuron resolution is described.
Daily briefing: The proteins that protect us from deadly mutations
Nature, Published online: 17 June 2026; doi:10.1038/d41586-026-01960-4Proteins that ‘buffer’ the effects of mutations could help to treat diseases such as cancers. Plus, goats can follow …
Analysis of 173,303 exomes and genomes in the Pakistan Genome Resource
Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10667-5The Pakistan Genome Resource compiles biobank data from 173,303 individuals with high familial relatedness, broadening the catalogue of human …
Confined migration induces non-lethal DNA damage in developing neurons
Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10648-8The migration of neurons in developing cerebral and cerebellar cortices is accompanied by massive DNA double-strand breaks due to …
A blastoporal organizer in a ctenophore
Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10643-zExperiments using the comb jelly Mnemiopsis leidyi and the sea anemone Nematostella vectensis reveal that the emergence of a …
Cortical development dynamics across autism spectrum disorder mouse models
Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10679-1Using single-nucleus multi-omic sequencing, diverse autism spectrum disorder-linked gene mutations converge on transient, stage-specific disruptions in early brain development, …
Rock weathering can counteract river CO<sub>2</sub> emissions induced by permafrost thaw
Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10664-8Permafrost thaw on the Qinghai–Tibet Plateau increases rock-weathering rates while reducing river CO2 emissions, suggesting geological carbon fluxes may …
Molecular basis of polyadenylated RNA fate determination in the nucleus
Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10650-0Biochemical, structural and cell biological analyses reveal that UAP56 (DDX39B) assembles with a TREX-2–like module that redirects non-functional polyadenylated …
Revealing competitive interfacial reactions in high-energy Li–S batteries
Nature, Published online: 17 June 2026; doi:10.1038/s41586-025-09473-2Visualization of concentration-driven phase segregation within high-concentration interfacial layers in the context of high-energy lithium–sulfur batteries using liquid-cell electrochemical …
Fast formation to reinforce lithium-rich cathodes
Nature, Published online: 17 June 2026; doi:10.1038/s41586-025-09553-3Fast formation in lithium-ion batteries outperforms conventional slow formation, lowering costs and improving battery capacity, stability and cycle life, …
A 98-qubit trapped-ion quantum computer with all-to-all connectivity
Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10676-4A new quantum computer, Quantinuum Helios, which is a 98-qubit trapped-ion quantum processor built on the QCCD architecture, demonstrates …
Structure of the pre-initiation complex explains CMGE biogenesis
Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10657-7Cryo-electron microscopy and biochemical reconstitution experiments in yeast provide insight into the assembly of the CMGE complex, a helicase …
A prototype differential atom interferometer for fundamental physics
Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10617-1A prototype differential atom interferometer operates at the standard quantum limit with no excess noise beyond atom shot noise, …
DNA from hunter-gatherer teeth reveals secrets of ancient plague
Nature, Published online: 17 June 2026; doi:10.1038/d41586-026-01941-7Analysis shows evidence of deadly outbreaks 5,500 years ago — plus, a prototype dark-matter detector.
The brain region that could provide a cognitive ‘reservoir’ in old age
Nature, Published online: 17 June 2026; doi:10.1038/d41586-026-01870-5Having a greater tissue volume in some parts of the cerebellum is linked to higher scores on cognitive tests.
Fiery data hint that controlled forest fires benefit human health
Nature, Published online: 17 June 2026; doi:10.1038/d41586-026-01868-zAnalysis of wildfire in California suggests a net reduction in exposure to blaze-related air pollution.
Freezing brain damage in its tracks: cooling drugs limit stroke injury in …
Nature, Published online: 17 June 2026; doi:10.1038/d41586-026-01923-9A two-drug combination induces hypothermia in mice by lowering metabolism and dilating blood vessels.
Optical fibre gripper for high-performance 3D micromanipulation
Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10673-7A miniature three-dimensional optical fibre gripper enables powerful, precise micromanipulation of particles and single cells in confined spaces, bridging …
Probing picometre-scale interlayer deformations via hyperbolic polaritons
Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10638-wA new polaritonic optical method that uses the mid-infrared out-of-plane hyperbolic polaritons mode is described and experimentally validated to …
A distant brown dwarf coplanar to a warm Jupiter and a hot …
Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10586-5Analysis of long-term radial velocity data and transit time variations, induced by a super-Earth, a warm Jupiter and a …
Emergent decadal predictability in Antarctic contribution to sea-level rise
Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10614-4Although Antarctic ice loss projections diverge widely by 2100, this Perspective shows that present-day rates robustly predict mid-century sea …
Towards Conversational AI for Disease Management
Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10764-5Towards Conversational AI for Disease Management
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