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Ductile alloys offering 100 MPa tensile strength at 2,400 °C
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10708-zA boron-stabilized oxide-strengthened tantalum alloy combines exceptional room-temperature ductility with record ultrahigh-temperature strength, enabling load-bearing applications above 2,000 °C.
Zero-shot design of drug-binding proteins via neural iterative selection−expansion
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10670-wBy pairing two neural networks in an iterative optimization algorithm, small-molecule binding proteins can be designed from scratch with …
Chiral laser gyroscopes breaking the lock-in limit
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10684-4Ring laser gyroscope lock-in has been eliminated using spontaneous symmetry breaking in a He–Ne laser, enabling accurate near-zero rotation …
GW250114 reveals signatures of post-merger black-hole horizon
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10696-0The observation of a direct wave after the merger of two black holes reveals signatures associated with the remnant …
Crude oil fractionation by means of mesoporous polyacrylonitrile membranes
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10677-3Porous polyacrylonitrile membranes—typically used as non-selective support layers—can be used to achieve effective molecular refining of crude oil at …
Genetic diversity of late Neanderthals in northwestern Europe
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10625-1Genetic sequencing of multiple late Neanderthals living less than 52,500 years ago provides an overview of genetic diversity and …
Fourier pixels for bidirectional light control
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10681-7A versatile platform of miniaturized Fourier-optics-based diffractive elements enables multifunctional pixels that fully control and sense the amplitude, phase …
Epiblast diversification and blood formation in a human pregastrula
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10698-yHigh-resolution spatial transcriptome analysis of a human embryo at Carnegie stage 6 reveals three distinct developmental trajectories from the …
An ECG biomarker for sudden cardiac death discovered with deep learning
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10674-6A deep-learning model trained on electrocardiogram (ECG) waveforms identifies an easily visible biomarker that predicts sudden cardiac death more …
Detection of anisotropic cosmic structures on a gigaparsec scale
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10702-5Using the parameter-free Angular Distribution of Pairwise Distances for measuring directional correlations, evidence is found for coherent anisotropic structures …
Optical cooling by interfacial charge transfer in 2D heterostructures
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10662-wOptical cooling in two-dimensional semiconductor heterostructures is demonstrated through phonon-assisted interfacial charge transfer, enabling cryogen-free thermal management without stringent …
Immunological mechanisms of mRNA vaccines for infectious diseases
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10599-0A Review of the immunological mechanisms of mRNA–lipid-nanoparticle vaccines for infectious diseases discusses how the components of this vaccine …
Small-molecule modulation of β-arrestins
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10683-5Integrated pharmacological, biochemical, biophysical and structural analyses of small-molecule β-arrestin inhibitors show how they block β-arrestin engagement with activated …
Disparate privacy risks from medical AI
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10688-0AI models for medical diagnostics are vulnerable to membership inference attacks.
Global high-resolution mapping of seagrass to support conservation
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10704-3Global high-resolution mapping shows widespread seagrass loss and degradation since 2019, with most meadows outside protected areas, highlighting urgent …
Dietary cholesterol activates a Ral-dependent pathway driving LDLR turnover
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10697-zChronic dietary cholesterol activates Ral GTPases, which promote LDLR internalization and lysosomal degradation through RalBP1–REPS1 and CTSA, thereby reducing …
Genetic technologies to enhance crop nutritional value under climate change
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10593-6This Review reflects on the joint power of genetic technologies, including untapped CRISPR–Cas techniques to combat hidden hunger and …
The mutational landscape of STING-induced immunity
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10685-3A massively parallel assay systematically charts the sequence-function landscape of the STING signalling protein, and the findings define molecular …
Volcanic magma sculpts eerie domes on the sea floor
Nature, Published online: 24 June 2026; doi:10.1038/d41586-026-01986-8Carbon dioxide bubbling up from underground material can solidify into formations of up to five metres tall.
AI tool spots antibiotics that fight drug-resistant gonorrhoea
Nature, Published online: 24 June 2026; doi:10.1038/d41586-026-01987-7The bacterium Neisseria gonorrhoeae has evolved resistance to most antibiotics used to treat it, but a machine-learning screen reveals …
Author Correction: cBAF complex components and MYC cooperate early in CD8<sup>+</sup> T …
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10813-zAuthor Correction: cBAF complex components and MYC cooperate early in CD8+ T cell fate
Medical records could be revealed by AI training-data vulnerability
Nature, Published online: 24 June 2026; doi:10.1038/d41586-026-02032-3Identification risks are more severe for underrepresented groups in the training data — plus, evidence that the Universe is …
On the robustness of topological gap detection via transport
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10567-8On the robustness of topological gap detection via transport
Addendum: Transmission of MPXV from fire-footed rope squirrels to sooty mangabeys
Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10767-2Addendum: Transmission of MPXV from fire-footed rope squirrels to sooty mangabeys
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