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Androgen activity in the male embryonic hindbrain drives lethal PFA ependymoma
Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10264-6Androgen activity in the male embryonic hindbrain prolongs hindbrain differentiation in male individuals and drives sex differences in the …
A fast starburst wind consumes most of the energy from supernovae
Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10231-1Starburst galaxies are seen to host galaxy-scale winds, which are super-fast and could be powered entirely by the thermal …
Structural energetics of cold sensitivity
Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10276-2Data from cryogenic electron microscopy combined with hydrogen–deuterium exchange mass spectrometry inform a mechanism for cold-evoked activation of the …
Topological soliton frequency comb in nanophotonic lithium niobate
Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10292-2An integrated lithium niobate–semiconductor platform generates topological soliton frequency combs on-chip, enabling turn-key, dispersion-agnostic comb sources without high-Q resonators …
Inactivating <i>SnRK1β1A</i> promotes broad-spectrum disease resistance in rice
Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10273-5SnRK1β1A in rice promotes susceptibility to multiple fungal diseases, and disrupting this infection-inducible gene confers broad-spectrum resistance without compromising …
Aversive learning hijacks a brain sugar sensor to consolidate memory
Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10306-zA study in Drosophilareveals a mechanism of non-homeostatic hunger and its critical relevance for memory consolidation.
Towards intelligent and miniaturized drug delivery devices
Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10221-3Intelligent and miniaturized drug delivery devices leveraging advances in biotechnology, artificial intelligence, electronics and materials science enable treatments with …
Functional hierarchy of the human neocortex across the lifespan
Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10219-xfMRI data from individuals of a wide range of ages (from a few days to 100 years old) are …
Exposed phosphatidylserine is an inhibitory molecule in T cell exhaustion
Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10266-4Insights into the mechanism by which phosphatidylserine functions as a non-classical inhibitory molecule during T cell exhaustion, and how …
Ectopic NMDAR expression in cancer unmasks germline-encoded autoimmunity
Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10278-0NMDAR expression is sufficient to induce B cell recruitment and affinity maturation, resulting in receptor-modulating antibodies that connect anti-cancer …
Dominant clones leverage developmental epigenomic states to drive ependymoma
Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10270-8Single-nucleus chromatin and RNA sequencing identifies epigenetic chromatin domains that confer vulnerability to paediatric brain tumours such as ependymomas, …
Genomic history of early dogs in Europe
Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10112-7Genome-wide analysis shows European dogs existed by 14,200 years ago, were already genetically distinct, received less Neolithic Southwest Asian …
Why insects aren't huge: a new challenge to a decades-old idea
Nature, Published online: 25 March 2026; doi:10.1038/d41586-026-00976-0Evidence suggests oxygen levels may not have been limiting factor — plus, CRISPR gives cancer-fighting immune cells an upgrade.
Retraction Note: Multisensory learning binds neurons into a cross-modal memory engram
Nature, Published online: 25 March 2026; doi:10.1038/s41586-026-10355-4Retraction Note: Multisensory learning binds neurons into a cross-modal memory engram
Why China’s philanthropists are digging deep for research
Nature, Published online: 25 March 2026; doi:10.1038/d41586-026-00424-zAn increase in donations, prizes and public–private initiatives suggests many firms want to show commitment to the government’s goals.
‘Continuity over novelty’: why environmental science needs to rethink its focus
Nature, Published online: 25 March 2026; doi:10.1038/d41586-026-00933-xWith government funding in decline, researchers should prioritize data collation and training the next generation of scientists.
Major conference catches illicit AI use — and rejects hundreds of papers
Nature, Published online: 25 March 2026; doi:10.1038/d41586-026-00893-2The papers’ watermarks allowed organizers to detect use of large language models in peer review.
China is an innovation powerhouse — but it should do more fundamental …
Nature, Published online: 25 March 2026; doi:10.1038/d41586-026-00935-9As the country looks to commercial companies to drive innovation, it has a golden opportunity to support open science …
Can China keep up its extraordinary research growth?
Nature, Published online: 25 March 2026; doi:10.1038/d41586-026-00423-0Evidence of a pivot towards other sources of funding and collaboration suggest it is looking for ways to maintain …
Earth may have formed from two separate rings around the sun
Our solar system’s rocky planets – Mercury, Venus, Earth and Mars – may have formed from two rings around the young sun, rather than a …
Cystitis or tooth decay could trigger dementia just a few years later
Infections are increasingly being linked to a higher risk of dementia. In the latest research, scientists have found that being treated in hospital for a …
The shocking fossils that show T. rex wasn't the king of the …
We've always thought that Tyrannosaurus rex was an unchallenged apex predator during the dying days of the dinosaurs. But a fresh look at controversial fossils …
Antimatter has been transported by road for the first time
CERN is working on building an antimatter delivery service. The project passed a big test by successfully transporting 92 antiprotons around a 4-kilometre loop of …
How AI shook the world's largest meeting of physicists
Physicists are grappling with how the increasing presence of AI will change the nature of their profession
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