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A metabolic alarmin from keratinocytes potentiates systemic humoral immunity
Nature, Published online: 04 March 2026; doi:10.1038/s41586-026-10167-6Farnesyl pyrophosphate—a mevalonate pathway metabolic intermediate—is an endogenous alarmin that enhances IgG antibody responses through keratinocyte-derived IL-6 and CCL20.
Limited thermal tolerance in tropical insects and its genomic signature
Nature, Published online: 04 March 2026; doi:10.1038/s41586-026-10155-wA survey of tropical insect populations and thermal tolerance limits indicates that species from lowland areas have low capacity …
DICER cleavage fidelity is governed by 5′-end binding pockets
Nature, Published online: 04 March 2026; doi:10.1038/s41586-026-10211-5Cryo-electron microscopy and massively parallel assays shed light on the mechanism by which DICER, a key enzyme in the …
Genome modelling and design across all domains of life with Evo 2
Nature, Published online: 04 March 2026; doi:10.1038/s41586-026-10176-5Evo 2 is an artificial intelligence-based biological foundation model trained on 9 trillion DNA base pairs spanning all domains …
Magnetic gel injected into the heart could stop strokes
Nature, Published online: 04 March 2026; doi:10.1038/d41586-026-00740-4The hydrogel-based plug blocks a part of the heart to cut stroke risk and was shown to be effective …
Heart surgery with quick-setting magnetic fluid could prevent strokes
Nature, Published online: 04 March 2026; doi:10.1038/d41586-026-00742-2Injectable fluid safely fills area in which blood clots can form, in animal trials — plus, strong evidence that …
Shared neural substrates of prosocial and parenting behaviours
Nature, Published online: 04 March 2026; doi:10.1038/s41586-026-10327-8Shared neural substrates of prosocial and parenting behaviours
Cancer blood tests are everywhere. Do they really work?
Nature, Published online: 04 March 2026; doi:10.1038/d41586-026-00661-2Their makers claim they can detect dozens of cancer types — but some scientists say they could be missing …
What snow monkeys’ steamy baths are really doing to their bodies
Japanese snow monkeys don’t just soak in hot springs to escape the winter chill — their steamy spa sessions may also be reshaping their invisible …
Scientists build a “periodic table” for AI
Choosing the right method for multimodal AI—systems that combine text, images, and more—has long been trial and error. Emory physicists created a unifying mathematical framework …
Scientists capture a magnetic flip in 140 trillionths of a second
Scientists at the University of Tokyo have captured something never seen before: a frame-by-frame view of how electron spins flip inside an antiferromagnet, a material …
This simple blood protein could stop a deadly black fungus
Scientists have uncovered a surprising new hero in the fight against one of the world’s deadliest fungal infections: albumin, the most abundant protein in human …
Wolves are stealing cougar kills in Yellowstone, study finds
In Yellowstone’s wild chess match between wolves and cougars, it turns out the real power play is theft. After tracking nearly a decade of GPS …
Phantom codes could help quantum computers avoid errors
A method for making quantum computers less error-prone could let them run complex programs such as simulations of materials more efficiently, thus making them more …
Laser printed hydrogel implant could transform bone repair
When a bone break is too severe to heal on its own, surgeons often rely on grafts or rigid metal implants — but both come …
Rare family has had many more sons than daughters for generations
Analysing the births of a Utah family over seven generations has revealed that their disproportionate number of boys could be caused by a selfish Y …
Selfish Y chromosome may explain why some families mostly have sons
A family in Utah with a disproportionate number of boys has been traced back over hundreds of years, revealing that its lack of female members …
Scientists find the genetic switch that makes pancreatic cancer resist chemotherapy
Scientists have identified a crucial molecular switch that decides whether pancreatic cancer cells resist chemotherapy or respond to it. The key player, a gene called …
The real reasons birth rates are declining worldwide
From the cost of childcare to the housing crisis, there’s no shortage of explanations for the dramatic global fall in the number of babies being …
Your microbiome may determine your risk of a severe allergic reaction
The microbes that live in our mouth and gut may influence whether an allergic reaction to peanuts is mild or life-threatening, and could be harnessed …
Intelligence emerges when the whole brain works as one
For decades, scientists have mapped attention, memory, language, and reasoning to separate brain networks — yet one big mystery remained: why does the mind feel …
Blasted off Mars and still alive
A famously resilient bacterium may be tough enough to survive one of the most violent events imaginable on Mars. In laboratory experiments designed to mimic …
James Webb spots a galaxy with tentacles in deep space
Astronomers using the James Webb Space Telescope have spotted the most distant “jellyfish galaxy” ever seen — a cosmic oddity streaming long, tentacle-like trails of …
A flash of laser light flips a magnet in major light-control breakthrough
Researchers at the University of Basel and the ETH in Zurich have succeeded in changing the polarity of a special ferromagnet using a laser beam. …
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