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I was set to lead an undergraduate research trip abroad. Then my …
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-00403-4Through flexibility, problem-solving and the generosity of colleagues, I shepherded students through fieldwork remotely.
Here are the top locations for cancer research in the Nature Index
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-00690-xA breakdown of publications in the database also reveals the cancer types with the highest output.
AI speeds up design of devices that turn waste heat into electricity
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-00907-zAn artificial-intelligence system bypasses complex equations to predict the performance of thermoelectric generators.
Four rising stars shaping the future of cancer research
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-00688-5Meet the creative minds that aim to improve cancer detection and treatment.
Composable neural emulators accelerate thermoelectric generator design
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10223-1A composable neural network emulator is described for speeding up thermoelectric generator design, demonstrating the ability to predict generator …
EBV strain interacts with host HLA to drive nasopharyngeal carcinoma risk
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10416-8A genome-to-genome association study identifies host and viral risk factors that interact to drive nasopharyngeal carcinoma endemicity in southern …
Mapping convergent regulators of melanoma drug resistance by PerturbFate
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10367-0PerturbFate is a high-throughput, cost-effective, single-cell platform that systematically profiles CRISPR interference perturbations to reveal common regulatory nodes and …
300-unit-per-second roll-to-roll manufacturing of visible metalenses
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10369-yThis work demonstrates industrial-scale roll-to-roll fabrication of high-efficiency visible metalenses using nanoimprinting and TiO2 coating, achieving low cost, high …
Pixelated quantum-dot superlattice LEDs
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10392-zScalable fabrication of ordered perovskite quantum dot superlattices enables high-efficiency, ultrahigh-resolution LEDs and active-matrix displays with greatly improved brightness, …
Language models transmit behavioural traits through hidden signals in data
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10319-8During model distillation, large language models can subtly transmit traits unrelated to the training data.
The neural mechanisms supporting the rise and fall of maternal aggression
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10354-5In mice, female aggression is governed by an amygdala–to–medial hypothalamus circuit that is strengthened during pregnancy and is dynamically …
Continuously tunable coherent pulse generation in a semiconductor laser
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10387-wA monolithic mode-locked semiconductor laser with a continuously and widely tunable repetition rate is achieved by using a microwave …
Template-driven scaffolding of SCF<sup>FBXO42</sup> regulates PP2A degradation
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10368-zThe E3 ligase SCFFBXO42 degrades holoenzyme-free PP2Ac in complex with the coiled-coil protein CCDC6 to maintain cancer cell fitness
Emergence of oncofetal plasticity is ubiquitous in early colorectal cancers
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10344-7Metastasis-associated oncofetal cell states emerge at the earliest stages of colorectal cancer and spatial profiling shows stereotypic patterning of …
Molecular basis for methylation-sensitive editing by Cas9
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10384-zThermoCas9, a genome-editing enzyme that is sensitive to the DNA methylation status of the target locus, is characterized and …
A mechanism for adaptive genome regulation in cancer
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10269-1In this Perspective article, a theoretical framework for how the AP-1 family of transcription factors mediates cellular adaptation in …
A spatial atlas of the healthy human liver from live donors
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10377-yA human spatial atlas of gene expression in liver based on live donors shows marked porto–central zonation of hepatocytes …
Cell-type-targeted mitochondrial transplantation rescues cell degeneration
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10391-0MitoCatch is a cell-type-specific mitochondrion-targeting system that links mitochondria and the cell surface by protein binders and delivers mitochondria …
Prospective evaluation of genomics-guided off-label treatment
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10405-xEvaluation by the Drug Rediscovery Protocol of off-label use of 37 approved cancer drugs on 1,610 patients showed modest …
mRNA vaccines engage unconventional pathways in CD8<sup>+</sup> T cell priming
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10353-6mRNA–lipid-nanoparticle vaccines do not require type 1 conventional dendritic (cDC1) cells or the WDFY4-dependent cross-presentation pathway for CD8+ T …
Tumour promotion through the lens of evolution
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10386-xThis Review revisits tumour initiation and promotion in light of clonal diversity and the presence of cancer driver mutations …
Ancient DNA reveals pervasive directional selection across West Eurasia
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10358-1Analysis of 15,836 ancient West Eurasian genomes reveals hundreds of instances of directional selection, showing that sustained changes in …
Brainwide blood volume reflects opposing neural populations
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10350-9Combined functional ultrasound imaging and Neuropixels recording of mouse brains identify two neuronal populations with opposing arousal-related activity and …
Identifying the topographic signature of early Martian oceans
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10381-2Shelves rather than shorelines may be better topographic indicators of oceans on Earth and Mars.
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