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Additive manufacturing of ultralong and architected single crystals
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11185-0A free-form additive manufacturing method that uses alternating and pulsed heat inputs is described for fabricating metre-tall, centimetre-diameter single …
Drought and disease trigger novel interactions among top predators
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11194-zClimate-driven drought and prey decline triggered lynx predation on raptors, reducing raptor fitness and abundance and producing cascading effects …
Touch-sensing digital pixel fibre enables interactive garment GUI
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11128-9Multifunctional digital fibres integrate display, touch sensing, computation and multimodal input–output, enabling flexible, washable garments with interactive graphical interfaces …
Functional architecture of the human insula
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11175-2A functional architecture of the human insula links cytoarchitecture to directed and asymmetric electrophysiological interactions, with mechanistic implications for …
The proteome of Middle Pleistocene Xujiayao and common Denisovan morphology
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11132-zDenisovans from the Xujiayao and other East Asian sites are morphologically distinctive, with a low cranial profile with near-parallel …
Amazon carbon emissions driven by human actions amplified by droughts
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11168-1Fifteen years of atmospheric CO2 measurements show that the Amazon carbon sink is weakening, with fires, deforestation and climate …
Octupole-driven spin torque switching of antiferromagnetic tunnel junctions
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11172-5All-antiferromagnetic tunnel junctions can display both a large TMR and a reciprocal switching effect, octupole-driven spin-transfer torque, enabling nanoscale …
Programmable design of functional proteins from natural language
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11205-zPinal, a 16-billion-parameter artificial intelligence model, designs functional proteins from natural-language descriptions, demonstrating experimentally validated activities and improved CO2-fixation …
GRP75-dependent SIMPA mediates inter-organellar quality control
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-10733-yProteotoxic stress drives formation of GRP75-dependent protein aggregates that signal through mitochondria–ER contact sites to activate targeted quality-control pathways, …
Structural basis for protocadherin-1 recognition by New World hantaviruses
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11184-1The structure of PCDH1 bound to the ANDV spike defines the structural determinants of hantavirus–receptor recognition.
Daily briefing: How tech billionaires are changing science funding
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03400-9Ultra-rich philanthropists are disrupting biomedical science. Plus, why physicists have kept an antimatter particle caged for months and whether …
Persistent neuronal stress signalling underlies Angelman syndrome phenotypes
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11165-4Genetic and proteomic analyses in human neurons and mouse models of Angelman syndrome (AS) show that loss of the …
CD51 delineates functionally distinct astrocyte subtypes in neural circuits
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11186-zCD51+ astrocytes promote synapse formation in the developing cortex, circuit plasticity in the hippocampus and circuit remodelling after stroke.
AI doctors’ orders come with a sky-high bill
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03320-8Large language models suggest more tests, referrals and medications than human physicians do, driving up the cost of care.
An environmentally regulated dichotomy in cell lineages of the root
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11179-yAn environment-regulated state is identified across multiple cell types at the root tip, revealing a shared dichotomy between cells …
A single archaeon couples long-chain fatty acid oxidation to methanogenesis
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11207-xMethanoglobus dolicholipophagus AA-75 is a thermophilic archaeon isolated from a Chinese petroleum reservoir that converts methanol into methane, carbon …
WEE1 opposes APC/C<sup>CDH1</sup> activity to promote S phase entry
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11188-xExperimental and modelling data indicate that WEE1 promotes re-entry of quiescent cells into the cell cycle, potentially explaining the …
Cold activates a BH2 metabolic network promoting longevity and proteostasis
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11152-9A multi-tissue signalling system links cold temperature to enhanced longevity and proteostasis in Caenorhabditis elegans.
Zeolite-catalysed olefin carbonylation based on tuning spatial confinement
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11183-2The use of zeolites with an appropriate pore structure combined with a high CO/olefin ratio is shown to catalyse …
The contribution of salt marshes to wave attenuation during extreme storms
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11145-8Salt marsh platforms resist erosion under extreme waves, but vegetation damage reduces wave attenuation; substantial wave attenuation by vegetation …
Multimodal precision diagnostics in clinical xenotransplantation
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11096-0Now that hyperacute rejection of pig xenografts can be reliably prevented, subtler immune-mediated graft injuries have emerged that conventional …
Fabric user interface can be worn on your sleeve — and machine-washed
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03064-5Touch-sensitive, light-emitting yarn can turn everyday clothing into washable, bendable user interfaces with dynamic graphics and versatile computing functions.
Robert Williamson obituary: geneticist who mapped genes for muscular dystrophy and cystic …
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03375-7Researcher and policy adviser who championed tests and treatments for genetic diseases.
A single antimatter particle in a cage opens door to ‘revolutionary’ physics
Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03342-2Physicists trap and cool down positron for months to measure its ‘magnetic moment’ with extraordinary precision.
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