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Restoring cortical disinhibition improves Huntington’s disease phenotypes
Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10671-9In a mouse model of Huntington’s disease, targeted modulation of neuronal activity restores network function and improves motor deficits.
Directly probing the carrier transfer length in 2D-material transistors
Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10707-0Cross-sectional scanning tunnelling microscopy shows a 2 nm carrier transfer length in bismuth-contacted monolayer MoS2 transistors, defining metal-contact scaling …
Targeted enzyme discovery using metal-coordination mining
Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10716-zA methodology for mining protein structure databases on the basis of the distinct intrinsic structures of metal-binding active sites …
Identification of cross-stage, cross-species malaria CD8<sup>+</sup> T cell antigens
Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10730-1An immunopeptidomics analysis identifies numerous Plasmodium T cell antigens that are conserved across malaria parasite species and expressed at …
Replication-stress-induced chromatin loops protect fork stability
Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10695-1Replication stress induces the formation of transient chromatin loops that enclose de novo heterochromatin-enriched stalled replication forks.
A secreted endosymbiont protein essential for colonizing host cells
Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10711-4SyeA was present in the Buchnera ancestor, is secreted into the host cytoplasm, is homologous to secreted effectors of …
Isomeric multi-hydrogen-bonding enables blue perovskite LEDs
Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10723-0Hydrogen-bonding networks engineered with isomeric molecules enable stable, saturated blue perovskite LEDs with record external quantum efficiencies up to …
Towards the construction of a virtual yeast
Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10574-9A virtual yeast, an artificial intelligence-driven agent for modelling eukaryotic cellular behaviours, is described.
Harmonizing standards and resources for the medical genome
Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10621-5This Perspective examines the challenges and opportunities of genomic sequencing across multiple clinical applications, including genetic therapies, and calls …
Backreaction of stimulated Hawking radiation in an optical analogue
Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10720-3By using a fibre-optical analogue of the physics of black holes, theoretical and experimental evidence is presented for the …
Togetherness: How cooperation built the world
Nature, Published online: 01 July 2026; doi:10.1038/d41586-026-02067-6Science journalist Rowan Hooper joins us to talk about symbiosis and the importance of organisms working together.
Daily briefing: How to brew a climate-friendly coffee
Nature, Published online: 30 June 2026; doi:10.1038/d41586-026-02076-5Researchers are racing to safeguard coffee from climate change. Plus, how ticks are making people allergic to meat and …
Coffee is under threat: how scientists are fighting to save it from …
Nature, Published online: 30 June 2026; doi:10.1038/d41586-026-01965-zCoffee plants are critically endangered by climate change. Researchers are finding solutions to keep scientists supplied with their favourite …
Can Rwanda sustain its rise in science and technology? Here’s what can …
Nature, Published online: 30 June 2026; doi:10.1038/d41586-026-01980-0An ambitious analysis challenges the view that a nation’s pursuit of economic growth alone can deliver long-term prosperity.
Early television set impresses Nature editors — but will it catch on?
Nature, Published online: 30 June 2026; doi:10.1038/d41586-026-01813-0Nature reports a demonstration of a ‘televisor’, and the British Government makes a generous endowment, in our weekly dip …
Enhanced B cell priming induces broadly neutralizing HIV-1 apex antibodies
Nature, Published online: 30 June 2026; doi:10.1038/s41586-026-10838-4Enhanced B cell priming induces broadly neutralizing HIV-1 apex antibodies
Retraction Note: NSD2 targeting reverses plasticity and drug resistance in prostate cancer
Nature, Published online: 30 June 2026; doi:10.1038/s41586-026-10816-wRetraction Note: NSD2 targeting reverses plasticity and drug resistance in prostate cancer
Vaccination elicits HIV broadly neutralizing antibodies in primates
Nature, Published online: 30 June 2026; doi:10.1038/s41586-026-10837-5Vaccination elicits HIV broadly neutralizing antibodies in primates
AI systems devise hypotheses and ways to test them
Nature, Published online: 30 June 2026; doi:10.1038/d41586-026-01873-2AI agents collaborate to generate biomedical hypotheses and analyse data, moving towards a laboratory discovery cycle with AI involved …
AI tools can speed up thinking, but evidence still comes from the …
Nature, Published online: 30 June 2026; doi:10.1038/d41586-026-02069-4AI tools can speed up thinking, but evidence still comes from the lab bench
Ebola preparedness must start with ecosystems and before humans show symptoms
Nature, Published online: 30 June 2026; doi:10.1038/d41586-026-02070-xEbola preparedness must start with ecosystems and before humans show symptoms
Child online safety needs more than social-media bans
Nature, Published online: 30 June 2026; doi:10.1038/d41586-026-02068-5Child online safety needs more than social-media bans
Ozone erosion started decades before the ozone hole’s discovery
Nature, Published online: 29 June 2026; doi:10.1038/d41586-026-02033-2Depletion of the ozone layer has been traced mainly to the widespread use of industrial chlorofluorocarbon chemicals, but there …
Daily briefing: Editing the epigenome with CRISPR to treat disease
Nature, Published online: 29 June 2026; doi:10.1038/d41586-026-02075-6CRISPR’s next act, the new ‘world’s fastest computer’ and how to triumph in the metaphorical penalty shootout of life.
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