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Assembly of helper NLR resistosome clusters upon activation of a coiled-coil NLR
Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10215-1SUMM2, a coiled-coil NLR, promotes the assembly of higher-order resistosome clusters to initiate cell death in plants.
Intestinal interoceptive dysfunction drives age-associated cognitive decline
Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10191-6Age-related microbiome changes increase medium-chain fatty acid-producing bacteria, driving GPR84-mediated myeloid inflammation, impaired vagal signalling and hippocampal dysfunction; targeting …
Snapshots of the dynamic basis of NTSR1 G protein subtype promiscuity
Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10120-7Time-resolved cryo-electron microscopy during activation of Gαi1βγ and Gα11βγ heterotrimers bound to NTSR1 enables isolation of multiple transient complexes …
Facile induction of immune tolerance by an interleukin-2–TGFβ surrogate agonist
Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10208-0A fusion protein designed to comprise IL-2 and a helminth-derived TGFβ mimic activates IL-2 and TGFβ signalling pathways in …
Lense–Thirring precessing magnetar engine drives a superluminous supernova
Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10151-0Observations of a nearby type I superluminous supernova showing oscillating light-curve bumps provide evidence of a centrally located magnetar …
Multimodal electron microscopy of halide perovskite interfacial dynamics
Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10238-8A multimodal in situ electron microscopy approach enables direct visualization of structural and chemical evolution in a working halide …
Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor
Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10240-0Marburgvirus glycoprotein binds to the endosomal receptor NPC1 in a distinct orientation with higher affinity compared with Ebola virus …
Multidimensional profiling of heterogeneity in supratentorial ependymomas
Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10214-2Individual supratentorial ependymoma tumour subgroups have two distinct progenitor-like cell states—neuroepithelial-like and embryonic-like—that are reminiscent of early human brain …
Capturing dynamic phage–pathogen coevolution by clinical surveillance
Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10136-zThe acquisition of a parasitic anti-phage mobile genetic element, PLE11, showing potent anti-phage activity against cocirculating ICP1, and the …
A large-scale coherent 4D imaging sensor
Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10183-6A 4D imaging architecture using a large-scale, coherent LiDAR focal plane array comprising more than 0.6 million photonic components …
The dynamic basis of G-protein recognition and activation by a GPCR
Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10228-wConventional and time-resolved cryo-electron microscopy reveal how NTSR1 dynamically engages and releases different G proteins, capturing over 20 intermediates …
This fish shouldn’t exist — the weird genetics of clonal vertebrates
Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00798-0A study reveals how the asexual Amazon molly defies evolutionary expectations — plus, evidence of what might be powering …
This supernova is too bright – now astronomers might know why
Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00801-8Wobbling signal could explain some extremely bright supernovae
‘Black rain’ in Tehran — what are the health effects?
Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00800-9Toxic smoke from burning oil depots has blanketed Iran’s capital following missile strikes.
Statistics reach a ‘crisis point’: nations struggle with a critical lack of …
Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00699-2Some researchers are sounding the alarm over the official data sets that track crucial aspects of life in the …
First bot, singular
Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00610-zFresh connections.
What is the science behind ‘science-backed’ supplements?
Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00707-5The task of decoding the research underlying the nutritional claims of health supplements is rarely straightforward.
Author Correction: Gut stem cell necroptosis by genome instability triggers bowel inflammation
Nature, Published online: 11 March 2026; doi:10.1038/s41586-026-10302-3Author Correction: Gut stem cell necroptosis by genome instability triggers bowel inflammation
Physics at risk: UK science leader on what’s wrong with the latest …
Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00757-9Paul Howarth, president of the Institute of Physics, says ‘constructive dialogue’ with the government is needed, or the country …
China pledges billion-dollar spending boost for science
Nature, Published online: 11 March 2026; doi:10.1038/d41586-026-00770-yFunding for national laboratories and important research projects would increase under the government’s plans.
Daily briefing: A daily multivitamin slows the signs of biological ageing
Nature, Published online: 10 March 2026; doi:10.1038/d41586-026-00792-6The daily supplement slows markers of ageing on two epigenetic ‘clocks’. Plus, the real science of skincare and the …
From cancer to Alzheimer’s: could a renewed focus on energy transform biomedicine?
Nature, Published online: 10 March 2026; doi:10.1038/d41586-026-00701-xIncluding energy dynamics in research could improve our understanding of diseases and of the healing processes that sustain health.
‘Virtual cell’ captures most-basic process of life: bacterial division
Nature, Published online: 10 March 2026; doi:10.1038/d41586-026-00786-4Researchers simulated nearly every molecule in a bacterial cell — and then watched the cell grow and reproduce.
Stop the use of AI in war until laws can be agreed
Nature, Published online: 10 March 2026; doi:10.1038/d41586-026-00762-yResearchers working on the most advanced AI models want rules to be drawn up to minimize the harm the …
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