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A guide to the Nature Index
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-00691-wA description of the terminology and methodology used in this supplement, and a guide to the functionality that is …
Global cancer rates are rising. How are countries reacting?
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-00689-4Denmark and South Korea stand out for their strong cancer strategies while England seeks to get back on track.
AI models ‘subliminally’ transmit biases when training other systems
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-01224-1Using artificial-intelligence to teach other models can be cheaper and faster than building them from scratch, but this approach …
Brain–machine interface reveals the origin of a widely used neural signal
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-01189-1A type of activity in the brain’s cortex, called high gamma, is widely used in studies of brain function, …
Molecular profiling of gene-edited cells reveals shared drug-resistance mechanisms
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-01181-9A platform for tracking the changes in gene expression and chromatin accessibility that follow interference with specific genes has …
Improving cancer survival rates will require hard policy choices
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-00686-7Integrated care and prevention strategies are key, but without careful planning — and sustainable funding — they risk falling …
I was set to lead an undergraduate research trip abroad. Then my …
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-00403-4Through flexibility, problem-solving and the generosity of colleagues, I shepherded students through fieldwork remotely.
Here are the top locations for cancer research in the Nature Index
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-00690-xA breakdown of publications in the database also reveals the cancer types with the highest output.
AI speeds up design of devices that turn waste heat into electricity
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-00907-zAn artificial-intelligence system bypasses complex equations to predict the performance of thermoelectric generators.
Four rising stars shaping the future of cancer research
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-00688-5Meet the creative minds that aim to improve cancer detection and treatment.
Composable neural emulators accelerate thermoelectric generator design
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10223-1A composable neural network emulator is described for speeding up thermoelectric generator design, demonstrating the ability to predict generator …
EBV strain interacts with host HLA to drive nasopharyngeal carcinoma risk
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10416-8A genome-to-genome association study identifies host and viral risk factors that interact to drive nasopharyngeal carcinoma endemicity in southern …
Mapping convergent regulators of melanoma drug resistance by PerturbFate
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10367-0PerturbFate is a high-throughput, cost-effective, single-cell platform that systematically profiles CRISPR interference perturbations to reveal common regulatory nodes and …
300-unit-per-second roll-to-roll manufacturing of visible metalenses
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10369-yThis work demonstrates industrial-scale roll-to-roll fabrication of high-efficiency visible metalenses using nanoimprinting and TiO2 coating, achieving low cost, high …
Pixelated quantum-dot superlattice LEDs
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10392-zScalable fabrication of ordered perovskite quantum dot superlattices enables high-efficiency, ultrahigh-resolution LEDs and active-matrix displays with greatly improved brightness, …
Language models transmit behavioural traits through hidden signals in data
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10319-8During model distillation, large language models can subtly transmit traits unrelated to the training data.
The neural mechanisms supporting the rise and fall of maternal aggression
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10354-5In mice, female aggression is governed by an amygdala–to–medial hypothalamus circuit that is strengthened during pregnancy and is dynamically …
Continuously tunable coherent pulse generation in a semiconductor laser
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10387-wA monolithic mode-locked semiconductor laser with a continuously and widely tunable repetition rate is achieved by using a microwave …
Template-driven scaffolding of SCF<sup>FBXO42</sup> regulates PP2A degradation
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10368-zThe E3 ligase SCFFBXO42 degrades holoenzyme-free PP2Ac in complex with the coiled-coil protein CCDC6 to maintain cancer cell fitness
Emergence of oncofetal plasticity is ubiquitous in early colorectal cancers
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10344-7Metastasis-associated oncofetal cell states emerge at the earliest stages of colorectal cancer and spatial profiling shows stereotypic patterning of …
Molecular basis for methylation-sensitive editing by Cas9
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10384-zThermoCas9, a genome-editing enzyme that is sensitive to the DNA methylation status of the target locus, is characterized and …
A mechanism for adaptive genome regulation in cancer
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10269-1In this Perspective article, a theoretical framework for how the AP-1 family of transcription factors mediates cellular adaptation in …
A spatial atlas of the healthy human liver from live donors
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10377-yA human spatial atlas of gene expression in liver based on live donors shows marked porto–central zonation of hepatocytes …
Cell-type-targeted mitochondrial transplantation rescues cell degeneration
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10391-0MitoCatch is a cell-type-specific mitochondrion-targeting system that links mitochondria and the cell surface by protein binders and delivers mitochondria …
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